Peripheral nerve involvement in spinocerebellar ataxias
BPC van de Warrenburg, NC Notermans… - Archives of …, 2004 - jamanetwork.com
Background In autosomal dominant cerebellar ataxias (ADCAs), it is unclear whether the
associated peripheral nerve involvement is always a typical length-dependent axonopathy
rather than primary neuronopathy due to neuronal degeneration in the spinal anterior horns
and/or dorsal root ganglia. Objective To study the nature and extent of peripheral nerve
involvement in patients with ADCA. Patients and Methods Standardized clinical and
electrophysiologic studies of 27 genotyped patients with ADCA were conducted …
associated peripheral nerve involvement is always a typical length-dependent axonopathy
rather than primary neuronopathy due to neuronal degeneration in the spinal anterior horns
and/or dorsal root ganglia. Objective To study the nature and extent of peripheral nerve
involvement in patients with ADCA. Patients and Methods Standardized clinical and
electrophysiologic studies of 27 genotyped patients with ADCA were conducted …