Mitochondrial dynamics contribute to the regulation of mitochondrial shape as well as
various mitochondrial functions and quality control. This is of particular interest in the beta-
cell because of the key role mitochondria play in the regulation of beta-cell insulin secretion
function. Moreover, mitochondrial dysfunction has been suggested to contribute to the
development of Type 2 Diabetes. Genetic tools that shift the balance of mitochondrial fusion
and fission result in alterations to beta-cell function and viability. Additionally, conditions that …