T follicular helper cells and HIV/SIV-specific antibody responses
C Petrovas, RA Koup - Current opinion in HIV and AIDS, 2014 - journals.lww.com
C Petrovas, RA Koup
Current opinion in HIV and AIDS, 2014•journals.lww.comThere are many ways in which HIV and SIV influence the complex signals and mechanisms
regulating the development of Tfh cells and their interactions with germinal center B cells.
Understanding the biology of Tfh cells will be necessary to appropriately recruit these cells
during vaccination with the goal of stimulating a more broad and potent neutralizing
antibody response.
regulating the development of Tfh cells and their interactions with germinal center B cells.
Understanding the biology of Tfh cells will be necessary to appropriately recruit these cells
during vaccination with the goal of stimulating a more broad and potent neutralizing
antibody response.
Summary
There are many ways in which HIV and SIV influence the complex signals and mechanisms regulating the development of Tfh cells and their interactions with germinal center B cells. Understanding the biology of Tfh cells will be necessary to appropriately recruit these cells during vaccination with the goal of stimulating a more broad and potent neutralizing antibody response.
Lippincott Williams & Wilkins