Disappearance of antibodies to SARS-associated coronavirus after recovery

WC Cao, W Liu, PH Zhang, F Zhang… - New England Journal …, 2007 - Mass Medical Soc
WC Cao, W Liu, PH Zhang, F Zhang, JH Richardus
New England Journal of Medicine, 2007Mass Medical Soc
To the Editor: Previous studies have demonstrated that IgG and neutralizing antibodies
against coronavirus associated with the severe acute respiratory syndrome (SARS) may
persist, in spite of a decline in titer, for 2 years in patients who have recovered from SARS. 1,
2 For 3 years, we followed patients who had recovered from infection with SARS-associated
coronavirus, to measure the longevity of specific antibodies. Fifty-six patients who were
positive for serum IgG and neutralizing antibodies against SARS-associated coronavirus at …
To the Editor: Previous studies have demonstrated that IgG and neutralizing antibodies against coronavirus associated with the severe acute respiratory syndrome (SARS) may persist, in spite of a decline in titer, for 2 years in patients who have recovered from SARS.1,2 For 3 years, we followed patients who had recovered from infection with SARS-associated coronavirus, to measure the longevity of specific antibodies.
Fifty-six patients who were positive for serum IgG and neutralizing antibodies against SARS-associated coronavirus at the time of recovery from acute SARS infection were included in this study.1 The titers of IgG and neutralizing antibodies were significantly . . .
The New England Journal Of Medicine