[HTML][HTML] Immunometabolism: cellular metabolism turns immune regulator

RM Loftus, DK Finlay - Journal of Biological Chemistry, 2016 - ASBMB
Immune cells are highly dynamic in terms of their growth, proliferation, and effector functions
as they respond to immunological challenges. Different immune cells can adopt distinct
metabolic configurations that allow the cell to balance its requirements for energy, molecular
biosynthesis, and longevity. However, in addition to facilitating immune cell responses, it is
now becoming clear that cellular metabolism has direct roles in regulating immune cell
function. This review article describes the distinct metabolic signatures of key immune cells …