[HTML][HTML] Pretransplant numbers of CD16+ monocytes as a novel biomarker to predict acute rejection after kidney transplantation: a pilot study
TPP Van den Bosch, LB Hilbrands… - American Journal of …, 2017 - Elsevier
Acute rejection is one of the major immunological determinants of kidney graft function and
survival. Early biomarkers to predict rejection are lacking. Emerging evidence reveals a
crucial role for the monocyte/macrophage lineage cells in the pathogenesis of rejection. We
hypothesized that higher pretransplant numbers of proinflammatory CD16+ monocytes can
predict rejection. The study cohort consisted of 104 kidney transplant recipients (58 with no
rejection and 46 with biopsy-proven rejection) and 33 healthy persons. Posttransplant …
survival. Early biomarkers to predict rejection are lacking. Emerging evidence reveals a
crucial role for the monocyte/macrophage lineage cells in the pathogenesis of rejection. We
hypothesized that higher pretransplant numbers of proinflammatory CD16+ monocytes can
predict rejection. The study cohort consisted of 104 kidney transplant recipients (58 with no
rejection and 46 with biopsy-proven rejection) and 33 healthy persons. Posttransplant …