Chemokine and chemokine receptor expression in paired peripheral blood mononuclear cells and synovial tissue of patients with rheumatoid arthritis, osteoarthritis …
JJ Haringman, TJM Smeets… - Annals of the rheumatic …, 2006 - Elsevier
Background: Chemokine receptors and chemokines have a crucial role in leucocyte
recruitment into inflamed tissue. Objective: To examine the expression of an extensive
number of chemokines and receptors in a unique bank of paired samples of synovial tissue
(ST) and peripheral blood (PB) from patients with different forms of arthritis to assist in
identifying suitable targets for therapeutic intervention. Methods: Synovial biopsy specimens
were obtained from 23 patients with rheumatoid arthritis (RA), 16 with osteoarthritis, and 8 …
recruitment into inflamed tissue. Objective: To examine the expression of an extensive
number of chemokines and receptors in a unique bank of paired samples of synovial tissue
(ST) and peripheral blood (PB) from patients with different forms of arthritis to assist in
identifying suitable targets for therapeutic intervention. Methods: Synovial biopsy specimens
were obtained from 23 patients with rheumatoid arthritis (RA), 16 with osteoarthritis, and 8 …