Isolating lymphocytes from the mouse small intestinal immune system

Z Qiu, BS Sheridan - JoVE (Journal of Visualized Experiments), 2018 - jove.com
The intestinal immune system plays an essential role in maintaining the barrier function of
the gastrointestinal tract by generating tolerant responses to dietary antigens and
commensal bacteria while mounting effective immune responses to enteropathogenic
microbes. In addition, it has become clear that local intestinal immunity has a profound
impact on distant and systemic immunity. Therefore, it is important to study how an intestinal
immune response is induced and what the immunologic outcome of the response is. Here, a …