Positron emission tomography-guided bone marrow-sparing radiation therapy for locoregionally advanced cervix cancer: final results from the INTERTECC phase II/III …

CW Williamson, I Sirák, R Xu, L Portelance… - International Journal of …, 2022 - Elsevier
Purpose To test effects of positron emission tomography (PET)–based bone marrow–
sparing (BMS) image-guided intensity modulated radiation therapy (IG-IMRT) on efficacy
and toxicity for patients with locoregionally advanced cervical cancer. Methods and
Materials In an international phase II/III trial, patients with stage IB-IVA cervical carcinoma
were treated with either PET-based BMS-IG-IMRT (PET-BMS-IMRT group) or standard
image-guided IMRT (IMRT group), with concurrent cisplatin (40 mg/m 2 weekly), followed by …