Thoracic vertebral body irradiation contributes to acute hematologic toxicity during chemoradiation therapy for non-small cell lung cancer
Purpose To determine the relationships between radiation doses to the thoracic bone
marrow and declines in blood cell counts in non-small cell lung cancer (NSCLC) patients
treated with chemoradiation therapy (CRT). Methods and Materials We included 52 patients
with NSCLC treated with definitive concurrent carboplatin–paclitaxel and RT. Dose-volume
histogram (DVH) parameters for the thoracic vertebrae (TV), sternum, scapulae, clavicles,
and ribs were assessed for associations with changes in blood counts during the course of …
marrow and declines in blood cell counts in non-small cell lung cancer (NSCLC) patients
treated with chemoradiation therapy (CRT). Methods and Materials We included 52 patients
with NSCLC treated with definitive concurrent carboplatin–paclitaxel and RT. Dose-volume
histogram (DVH) parameters for the thoracic vertebrae (TV), sternum, scapulae, clavicles,
and ribs were assessed for associations with changes in blood counts during the course of …