Transcript abundance patterns in Kawasaki disease patients with intravenous immunoglobulin resistance
W Fury, AH Tremoulet, VE Watson, BM Best… - Human immunology, 2010 - Elsevier
Intravenous immunoglobulin (IVIG)–resistant Kawasaki disease (KD) patients comprise at
least 20% of treated patients and are at high risk for coronary artery abnormalities. If
identified early in the course of the disease, such patients may benefit from additional anti-
inflammatory therapy. The aim of this study was to compare the transcript abundance
between IVIG resistant and-responsive KD patients, to identify biomarkers that might
differentiate between these two groups and to generate new targets for therapies in IVIG …
least 20% of treated patients and are at high risk for coronary artery abnormalities. If
identified early in the course of the disease, such patients may benefit from additional anti-
inflammatory therapy. The aim of this study was to compare the transcript abundance
between IVIG resistant and-responsive KD patients, to identify biomarkers that might
differentiate between these two groups and to generate new targets for therapies in IVIG …