Changes in blood lipids during six days of overfeeding with medium or long chain triglycerides.

JO Hill, JC Peters, LL Swift, D Yang, T Sharp… - Journal of lipid …, 1990 - ASBMB
Although medium chain triglyceride (MCT) is less calorically dense than long chain
triglyceride (LCT), it produces a greater thermic effect following ingestion. We hypothesized
that the previously observed high rate of thermogenesis produced by MCT overfeeding was
due to hepatic de novo synthesis of long chain fatty acids (LCFA) from the excess medium
chain fatty acids (MCFA). To study this, we compared the effects of overfeeding MCT-and
LCT-containing diets on blood lipid profiles. Ten in-patient, nonobese males were overfed …