[HTML][HTML] Urinary NGAL as a diagnostic and prognostic marker for acute kidney injury in cirrhosis: a prospective study
AS Allegretti, XV Parada, P Endres… - Clinical and …, 2021 - journals.lww.com
METHODS: Urinary NGAL was measured in a prospective cohort of 213 US hospitalized
patients with decompensated cirrhosis (161 with AKI and 52 reference patients without AKI).
NGAL was assessed for its ability to discriminate ATN from non-ATN AKI and to predict 90-
day outcomes. RESULTS: Among patients with AKI, 57 (35%) had prerenal AKI, 55 (34%)
had HRS, and 49 (30%) had ATN, with a median serum creatinine of 2.0 (interquartile range
1.5, 3.0) mg/dL at enrollment. At an optimal cutpoint of 244 μg/g creatinine, NGAL …
patients with decompensated cirrhosis (161 with AKI and 52 reference patients without AKI).
NGAL was assessed for its ability to discriminate ATN from non-ATN AKI and to predict 90-
day outcomes. RESULTS: Among patients with AKI, 57 (35%) had prerenal AKI, 55 (34%)
had HRS, and 49 (30%) had ATN, with a median serum creatinine of 2.0 (interquartile range
1.5, 3.0) mg/dL at enrollment. At an optimal cutpoint of 244 μg/g creatinine, NGAL …