Flow dynamics of human sickle erythrocytes in the mesenteric microcirculation of the exchange-transfused rat
J Kurantsin-Mills, HM Jacobs, PP Klug, LS Lessin - Microvascular research, 1987 - Elsevier
To analyze the microvascular rheology of sickle cells in an intact animal model, rats were
isovolemically exchange transfused with human normal (hemoglobin AA) or sickle
(hemoglobin SS) erythrocytes (blood group O) or autologous red cells under ambient
conditions, and the effects of the heterologous or autologous cells on (a) hemodynamics and
respiration,(b) blood gases, and (c) acid-base status of the recipients were determined.
Exchange transfusion of rats with autologous red cells or hemoglobin AA or hemoglobin SS …
isovolemically exchange transfused with human normal (hemoglobin AA) or sickle
(hemoglobin SS) erythrocytes (blood group O) or autologous red cells under ambient
conditions, and the effects of the heterologous or autologous cells on (a) hemodynamics and
respiration,(b) blood gases, and (c) acid-base status of the recipients were determined.
Exchange transfusion of rats with autologous red cells or hemoglobin AA or hemoglobin SS …