From neutrophil extracellular traps release to thrombosis: an overshooting host‐defense mechanism?
JI Borissoff, H Ten Cate - Journal of thrombosis and haemostasis, 2011 - jthjournal.org
Innate immunity and blood coagulation are evolutionary entangled in an intricate network of
molecular and cellular interactions, thus forming an integral part of the host-defense system
[1]. Polymorphonuclear cells, in particular neutrophils, are essential for the primary innate
immune response against local and systemic infections or tissue injury [2], but are also
major cellular mediators supporting inflammation–coagulation interactions [3]. Upon
inflammation, multiple chemotactic stimuli (cytokines, chemokines, etc.) are released to …
molecular and cellular interactions, thus forming an integral part of the host-defense system
[1]. Polymorphonuclear cells, in particular neutrophils, are essential for the primary innate
immune response against local and systemic infections or tissue injury [2], but are also
major cellular mediators supporting inflammation–coagulation interactions [3]. Upon
inflammation, multiple chemotactic stimuli (cytokines, chemokines, etc.) are released to …