Cytokine abundance in placental tissues: evidence of inflammatory activation in gestational membranes with term and preterm parturition

JA Keelan, KW Marvin, TA Sato, M Coleman… - American journal of …, 1999 - Elsevier
Objectives: This study of the changes in cytokine concentrations in gestational tissues from
women with term and preterm labor was undertaken to assess the extent of inflammatory
activation associated with spontaneous labor and delivery. Study Design: Extracts of
amniotic, chorionic-decidual, and placental tissues from women delivered at term before
labor (n= 15), at term after labor (n= 15), and preterm (n= 31) were assayed for interleukin
1β, interleukin 6, and interleukin 8. Results: In amniotic tissues of women delivered by …