The safety and efficacy of sublingual and oral immunotherapy for milk allergy
CA Keet, PA Frischmeyer-Guerrerio… - Journal of Allergy and …, 2012 - Elsevier
BACKGROUND: Oral immunotherapy (OIT) and sublingual immunotherapy (SLIT) are
potential therapies for food allergy, but the optimal method of administration, mechanism of
action, and duration of response remain unknown. OBJECTIVE: We sought to explore the
safety and efficacy of OIT and SLIT for the treatment of cow's milk (CM) allergy. METHODS:
We randomized children with CM allergy to SLIT alone or SLIT followed by OIT. After
screening double-blind, placebo-controlled food challenges and initial SLIT escalation …
potential therapies for food allergy, but the optimal method of administration, mechanism of
action, and duration of response remain unknown. OBJECTIVE: We sought to explore the
safety and efficacy of OIT and SLIT for the treatment of cow's milk (CM) allergy. METHODS:
We randomized children with CM allergy to SLIT alone or SLIT followed by OIT. After
screening double-blind, placebo-controlled food challenges and initial SLIT escalation …