[HTML][HTML] Novel insights into the immunomodulatory role of the dendritic cell and macrophage-expressed C-type lectin MGL

Y van Kooyk, JM Ilarregui, SJ van Vliet - Immunobiology, 2015 - Elsevier
Based on their ability to balance tolerance and inflammation, antigen presenting cells, such
as dendritic cells and macrophages contribute to the maintenance of immune homeostasis
as well as the instigation of immune activation. Acting as key sensors of tissue integrity and
pathogen invasion, they are well equipped with a wide variety of pattern recognition
receptors, to which the C-type lectin family also belongs. C-type lectins are glycan-binding
receptors that mediate cell–cell communication and pathogen recognition, besides …