Hypoglycemic episodes and risk of dementia in older patients with type 2 diabetes mellitus
RA Whitmer, AJ Karter, K Yaffe, CP Quesenberry… - Jama, 2009 - jamanetwork.com
Context Although acute hypoglycemia may be associated with cognitive impairment in
children with type 1 diabetes, no studies to date have evaluated whether hypoglycemia is a
risk factor for dementia in older patients with type 2 diabetes. Objective To determine if
hypoglycemic episodes severe enough to require hospitalization are associated with an
increased risk of dementia in a population of older patients with type 2 diabetes followed up
for 27 years. Design, Setting, and Patients A longitudinal cohort study from 1980-2007 of 16 …
children with type 1 diabetes, no studies to date have evaluated whether hypoglycemia is a
risk factor for dementia in older patients with type 2 diabetes. Objective To determine if
hypoglycemic episodes severe enough to require hospitalization are associated with an
increased risk of dementia in a population of older patients with type 2 diabetes followed up
for 27 years. Design, Setting, and Patients A longitudinal cohort study from 1980-2007 of 16 …