Alpha1-Antitrypsin Deficiency

P Strnad, NG McElvaney… - New England Journal of …, 2020 - Mass Medical Soc
New England Journal of Medicine, 2020Mass Medical Soc
Alpha1-Antitrypsin Deficiency AAT is a protease inhibitor targeting neutrophil elastase. It
prevents the destruction of tissue, particularly in the lung, from elastase activity. AAT
deficiency is a genetic disorder characterized by pulmonary disease, especially emphysema
and bronchiectasis, and hepatic disease.
Alpha1-Antitrypsin Deficiency
AAT is a protease inhibitor targeting neutrophil elastase. It prevents the destruction of tissue, particularly in the lung, from elastase activity. AAT deficiency is a genetic disorder characterized by pulmonary disease, especially emphysema and bronchiectasis, and hepatic disease.
The New England Journal Of Medicine