Transferrin concentrations in serum and lower respiratory tract fluid of mechanically ventilated patients with COPD or ARDS

SW Stites, ME Nelson, LJ Wesselius - Chest, 1995 - Elsevier
Transferrin serves as the primary iron transport protein in serum, but it also is present in the
lower respiratory tract where it has antioxidant and antibacterial properties. Prior studies
indicate that patients with respiratory failure (RF) due to ARDS have increased
concentrations of transferrin in the lower respiratory tract, which is attributed to increased
lung vascular permeability. It is unclear whether mechanical ventilation contributes to
increased lung transferrin content in patients with ARDS, although mechanical ventilation …