Total pancreatectomy with islet autotransplantation may be indicated for adult and pediatric
patients with intractable symptoms of chronic or recurrent acute pancreatitis that lack
conventional surgical alternatives. Small duct chronic pancreatitis and hereditary
pancreatitis syndromes are the most successful settings in which this approach has been
applied. Preservation of pancreatic endocrine function by autotransplantation of islets via the
portal vein may improve postoperative glycemic management and, in approximately one …