Phosphatidylinositol 4-kinase β is required for the ciliogenesis of zebrafish otic vesicle
Y Feng, P Yu, J Li, Y Cao, J Zhang - Journal of Genetics and Genomics, 2020 - Elsevier
The primary cilium, an important microtubule-based organelle, protrudes from nearly all the
vertebrate cells. The motility of cilia is necessary for various developmental and
physiological processes. Phosphoinositides (PIs) and its metabolite, PtdIns (4, 5) P2, have
been revealed to contribute to cilia assembly and disassembly. As an important kinase of the
PI pathway and signaling, phosphatidylinositol 4-kinase β (PI4KB) is the one of the most
extensively studied phosphatidylinositol 4-kinase isoform. However, its potential roles in …
vertebrate cells. The motility of cilia is necessary for various developmental and
physiological processes. Phosphoinositides (PIs) and its metabolite, PtdIns (4, 5) P2, have
been revealed to contribute to cilia assembly and disassembly. As an important kinase of the
PI pathway and signaling, phosphatidylinositol 4-kinase β (PI4KB) is the one of the most
extensively studied phosphatidylinositol 4-kinase isoform. However, its potential roles in …