Age-related decreases in endocochlear potential are associated with vascular abnormalities in the stria vascularis

MA Gratton, RA Schmiedt, BA Schulte - Hearing research, 1996 - Elsevier
The density and diameter of strial capillaries were assessed in whole-mount preparations of
the cochlear lateral wall from 18 gerbils aged in quiet for at least 36 months. Following
morphometric analysis, histopathologic changes in selected regions of the lateral wall were
examined by light and transmission electron microscopy. Alterations in strial vasculature
were compared with the endocochlear potential (EP) measurements from the same ear.
Vascular degeneration occurred in a segmental fashion in that regions of atrophic capillaries …