[PDF][PDF] Epithelial homeostasis: elimination by live cell extrusion
H Katoh, Y Fujita - Current Biology, 2012 - cell.com
H Katoh, Y Fujita
Current Biology, 2012•cell.comEpithelial Homeostasis: Elimination by Live Cell Extrusion Page 1 The ‘species problem’ is to
find a biological process that underwrites and makes ‘natural’ some particular pattern or
extent of clustering, telling us what in general a species is and how to recognize one [7]. But if
multiple and indeed potentially opposed processes are driving bacterial population genomic
evolution with variable intensities and consequences, then there is no reason to expect that
all bacteria will belong to clusters at any specified level of cohesiveness, and no non-arbitrary …
find a biological process that underwrites and makes ‘natural’ some particular pattern or
extent of clustering, telling us what in general a species is and how to recognize one [7]. But if
multiple and indeed potentially opposed processes are driving bacterial population genomic
evolution with variable intensities and consequences, then there is no reason to expect that
all bacteria will belong to clusters at any specified level of cohesiveness, and no non-arbitrary …
Summary
To maintain a functional and harmonious epithelial society, the number and quality of cells need to be tightly controlled. Two recent studies reveal a novel cellular process for epithelial homeostasis: crowding-mediated live cell extrusion.
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