Innate immunity: impact on the adaptive immune response
R Medzhitov, CA Janeway Jr - Current opinion in immunology, 1997 - Elsevier
R Medzhitov, CA Janeway Jr
Current opinion in immunology, 1997•ElsevierFor many years, innate immunity has been considered as a separate entity from the adaptive
immune response and has been regarded to be of secondary importance in the hierarchy of
immune functions. For the past few years, however, interest in innate immunity has grown
enormously, so that now it is studied intensively in many laboratories that seek to integrate
these two distinct types of immune function. Our intent in this review is to point out the
similarities and differences in these two types of host response to infection, and to indicate …
immune response and has been regarded to be of secondary importance in the hierarchy of
immune functions. For the past few years, however, interest in innate immunity has grown
enormously, so that now it is studied intensively in many laboratories that seek to integrate
these two distinct types of immune function. Our intent in this review is to point out the
similarities and differences in these two types of host response to infection, and to indicate …
For many years, innate immunity has been considered as a separate entity from the adaptive immune response and has been regarded to be of secondary importance in the hierarchy of immune functions. For the past few years, however, interest in innate immunity has grown enormously, so that now it is studied intensively in many laboratories that seek to integrate these two distinct types of immune function. Our intent in this review is to point out the similarities and differences in these two types of host response to infection, and to indicate our present level of understanding of how these can be integrated into a more complete description of the immune response.
Elsevier