[CITATION][C] Know Thy Enemy—Understanding the Role of Inflammation in Severe Acute Pancreatitis
Acute pancreatitis (AP), an inflammatory disease of the pancreas, is one of the most
common gastrointestinal disease responsible for hospital admission, morbidity, and
mortality. 1 There is no specific therapy for these patients and even today treatment
continues to be largely supportive. This lack of progress stems from gaps in our
understanding of the pathogenesis of AP. 2, 3 Progression of pancreatitis can be broadly
divided into 2 phases. An intra-acinar phase, where injury and inflammation is initiated in the …
common gastrointestinal disease responsible for hospital admission, morbidity, and
mortality. 1 There is no specific therapy for these patients and even today treatment
continues to be largely supportive. This lack of progress stems from gaps in our
understanding of the pathogenesis of AP. 2, 3 Progression of pancreatitis can be broadly
divided into 2 phases. An intra-acinar phase, where injury and inflammation is initiated in the …
