Stereology is of great value for better understanding the pathomorphogenesis of benign
prostatic hyperplasia (BPH) and the hormonally controlled mechanism of abnormal over-
growth of the prostate gland, especially the stromal component. In human BPH a fourfold
absolute increase of the stromal part and a nearly double increase of the glandular part is
indicated. The relative and absolute increase of the stromal part is surprisingly constant in
spite of variation of human BPH. Stromal overgrowth can be viewed as a central feature of …