Square root transformation of geographic atrophy area measurements to eliminate dependence of growth rates on baseline lesion measurements: a reanalysis of age …
WJ Feuer, Z Yehoshua, G Gregori, FM Penha… - JAMA …, 2013 - jamanetwork.com
Methods Area measurements of GA collected from 181 eyes of 181 AREDS study patients
and followed up longitudinally for up to 4 years were analyzed using the square root
transformation strategy. 2 The correlations between growth of the lesion area over 4 years
and baseline lesion size were performed on the original area scale and on the square root
area scale with both Pearson and Spearman correlation analyses. In a second analysis,
lesions were divided into the published categories of baseline lesion size expressed as disc …
and followed up longitudinally for up to 4 years were analyzed using the square root
transformation strategy. 2 The correlations between growth of the lesion area over 4 years
and baseline lesion size were performed on the original area scale and on the square root
area scale with both Pearson and Spearman correlation analyses. In a second analysis,
lesions were divided into the published categories of baseline lesion size expressed as disc …
