Importance Thrombotic events are commonly reported in critically ill patients with COVID-19.
Limited data exist to guide the intensity of antithrombotic prophylaxis. Objective To evaluate
the effects of intermediate-dose vs standard-dose prophylactic anticoagulation among
patients with COVID-19 admitted to the intensive care unit (ICU). Design, Setting, and
Participants Multicenter randomized trial with a 2× 2 factorial design performed in 10
academic centers in Iran comparing intermediate-dose vs standard-dose prophylactic …