The innate immune system orchestrated by leukocytes primarily neutrophils, serves to
remove dead and dying host cells and to provide protection against invasion by pathogens.
Failure of this system results in the onset of sepsis leading to grave consequences for the
host. Together with mechanical methods to physically isolate and remove the pathogen,
neutrophils also release an important set of proinflammatory biological modulators that
mediate recruitment of additional cells to a site of infection and amplify the innate protective …