Determining the incidence of asymptomatic SARS-CoV-2 among early recipients of COVID-19 vaccines (DISCOVER-COVID-19): a prospective cohort study of …
CM North, A Barczak, RH Goldstein… - Clinical Infectious …, 2022 - academic.oup.com
Clinical Infectious Diseases, 2022•academic.oup.com
The impact of coronavirus disease 2019 vaccination on viral characteristics of breakthrough
infections is unknown. In this prospective cohort study, incidence of severe acute respiratory
syndrome coronavirus 2 infection decreased following vaccination. Although asymptomatic
positive tests were observed following vaccination, the higher cycle thresholds, repeat
negative tests, and inability to culture virus raise questions about their clinical significance.
infections is unknown. In this prospective cohort study, incidence of severe acute respiratory
syndrome coronavirus 2 infection decreased following vaccination. Although asymptomatic
positive tests were observed following vaccination, the higher cycle thresholds, repeat
negative tests, and inability to culture virus raise questions about their clinical significance.
Abstract
The impact of coronavirus disease 2019 vaccination on viral characteristics of breakthrough infections is unknown. In this prospective cohort study, incidence of severe acute respiratory syndrome coronavirus 2 infection decreased following vaccination. Although asymptomatic positive tests were observed following vaccination, the higher cycle thresholds, repeat negative tests, and inability to culture virus raise questions about their clinical significance.
Oxford University Press