Role of vitamin E in preventing the oxidation of low-density lipoprotein
H Esterbauer, M Dieber-Rotheneder, G Striegl… - The American journal of …, 1991 - Elsevier
The fatty acid composition, antioxidants, and the oxidation resistance of the low-density
lipoproteins (LDL) from a number of different donors were determined. The oxidation
resistance of LDL, as determined in vitro by the duration of the lag-phase in copper ion-
induced oxidation, did not correlate with the α-tocopherol content of the LDL. By
supplementating plasma with vitamin E, the a-tocopherol content of LDL could be increased
from∼ 9 to 30 mol/mol LDL and also the oxidative resistance increased nearly linearly with …
lipoproteins (LDL) from a number of different donors were determined. The oxidation
resistance of LDL, as determined in vitro by the duration of the lag-phase in copper ion-
induced oxidation, did not correlate with the α-tocopherol content of the LDL. By
supplementating plasma with vitamin E, the a-tocopherol content of LDL could be increased
from∼ 9 to 30 mol/mol LDL and also the oxidative resistance increased nearly linearly with …