Effect of fresh vs standard-issue red blood cell transfusions on multiple organ dysfunction syndrome in critically ill pediatric patients: a randomized clinical trial
PC Spinella, M Tucci, DA Fergusson, J Lacroix… - Jama, 2019 - jamanetwork.com
Importance The clinical consequences of red blood cell storage age for critically ill pediatric
patients have not been examined in a large, randomized clinical trial. Objective To
determine if the transfusion of fresh red blood cells (stored≤ 7 days) reduced new or
progressive multiple organ dysfunction syndrome compared with the use of standard-issue
red blood cells in critically ill children. Design, Setting, and Participants The Age of
Transfused Blood in Critically-Ill Children trial was an international, multicenter, blinded …
patients have not been examined in a large, randomized clinical trial. Objective To
determine if the transfusion of fresh red blood cells (stored≤ 7 days) reduced new or
progressive multiple organ dysfunction syndrome compared with the use of standard-issue
red blood cells in critically ill children. Design, Setting, and Participants The Age of
Transfused Blood in Critically-Ill Children trial was an international, multicenter, blinded …