Resident and recruited macrophages are key players in the homeostatic function of the liver
and in its response to tissue damage. In response to environmental signals, macrophages
undergo polarized activation to M1 or M2 or M2-like activation states. These are extremes of
a spectrum in a universe of activation states. Progress has been made in understanding the
molecular mechanisms underlying the polarized activation of mononuclear phagocytes.
Resident and recruited macrophages are a key component of diverse homeostatic and …