Effects of maternal leptin treatment during lactation on the body weight and leptin resistance of adult offspring
MC Lins, EG de Moura, PC Lisboa, IT Bonomo… - Regulatory peptides, 2005 - Elsevier
We investigate whether leptin treatment to lactating rats affects food intake, body weight and
leptin serum concentration and its anorectic effect on their adult offspring. Lactating rats
were divided into 2 groups: Lep-single injected with recombinant rat leptin (8 μg/100 g of
body weight, daily for the last 3 consecutive days of lactation) and control group (C) that
received the same volume of saline. After weaning all pups had free access to the control
diet, their body weight and food intake were monitored at each 4 days until 180 days of age …
leptin serum concentration and its anorectic effect on their adult offspring. Lactating rats
were divided into 2 groups: Lep-single injected with recombinant rat leptin (8 μg/100 g of
body weight, daily for the last 3 consecutive days of lactation) and control group (C) that
received the same volume of saline. After weaning all pups had free access to the control
diet, their body weight and food intake were monitored at each 4 days until 180 days of age …