[HTML][HTML] Antibody responses to SARS-CoV-2 in patients with COVID-19
QX Long, BZ Liu, HJ Deng, GC Wu, K Deng, YK Chen… - Nature medicine, 2020 - nature.com
QX Long, BZ Liu, HJ Deng, GC Wu, K Deng, YK Chen, P Liao, JF Qiu, Y Lin, XF Cai…
Nature medicine, 2020•nature.comWe report acute antibody responses to SARS-CoV-2 in 285 patients with COVID-19. Within
19 days after symptom onset, 100% of patients tested positive for antiviral immunoglobulin-G
(IgG). Seroconversion for IgG and IgM occurred simultaneously or sequentially. Both IgG
and IgM titers plateaued within 6 days after seroconversion. Serological testing may be
helpful for the diagnosis of suspected patients with negative RT–PCR results and for the
identification of asymptomatic infections.
19 days after symptom onset, 100% of patients tested positive for antiviral immunoglobulin-G
(IgG). Seroconversion for IgG and IgM occurred simultaneously or sequentially. Both IgG
and IgM titers plateaued within 6 days after seroconversion. Serological testing may be
helpful for the diagnosis of suspected patients with negative RT–PCR results and for the
identification of asymptomatic infections.
Abstract
We report acute antibody responses to SARS-CoV-2 in 285 patients with COVID-19. Within 19 days after symptom onset, 100% of patients tested positive for antiviral immunoglobulin-G (IgG). Seroconversion for IgG and IgM occurred simultaneously or sequentially. Both IgG and IgM titers plateaued within 6 days after seroconversion. Serological testing may be helpful for the diagnosis of suspected patients with negative RT–PCR results and for the identification of asymptomatic infections.
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