Isolation of infectious SARS-CoV-2 from urine of a COVID-19 patient
J Sun, A Zhu, H Li, K Zheng, Z Zhuang… - Emerging microbes & …, 2020 - Taylor & Francis
J Sun, A Zhu, H Li, K Zheng, Z Zhuang, Z Chen, Y Shi, Z Zhang, S Chen, X Liu, J Dai, X Li…
Emerging microbes & infections, 2020•Taylor & FrancisABSTRACT SARS-CoV-2 caused a major outbreak of severe pneumonia (COVID-19) in
humans. Viral RNA was detected in multiple organs in COVID-19 patients. However,
infectious SARS-CoV-2 was only isolated from respiratory specimens. Here, infectious
SARS-CoV-2 was successfully isolated from urine of a COVID-19 patient. The virus isolated
could infect new susceptible cells and was recognized by its' own patient sera. Appropriate
precautions should be taken to avoid transmission from urine.
humans. Viral RNA was detected in multiple organs in COVID-19 patients. However,
infectious SARS-CoV-2 was only isolated from respiratory specimens. Here, infectious
SARS-CoV-2 was successfully isolated from urine of a COVID-19 patient. The virus isolated
could infect new susceptible cells and was recognized by its' own patient sera. Appropriate
precautions should be taken to avoid transmission from urine.
Abstract
SARS-CoV-2 caused a major outbreak of severe pneumonia (COVID-19) in humans. Viral RNA was detected in multiple organs in COVID-19 patients. However, infectious SARS-CoV-2 was only isolated from respiratory specimens. Here, infectious SARS-CoV-2 was successfully isolated from urine of a COVID-19 patient. The virus isolated could infect new susceptible cells and was recognized by its’ own patient sera. Appropriate precautions should be taken to avoid transmission from urine.
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