Lower skeletal muscle capillarization in hypertensive elderly men

M Gueugneau, C Coudy-Gandilhon, B Meunier… - Experimental …, 2016 - Elsevier
Aging strongly affects the skeletal muscle and is associated with microvascular dysfunctions.
Age is also a primary risk factor for the metabolic syndrome, which is a cluster of metabolic
and cardiovascular symptoms. Among the metabolic syndrome components, hypertension is
the most prevalent in elderly subjects and has a central role in vascular alterations. Despite
critical clinical outcomes, the effects of hypertension and metabolic syndrome on skeletal
muscle capillarization have poorly been investigated during aging. In the present study …