Epilepsy in Duchenne and Becker muscular dystrophies
F Goodwin, F Muntoni, V Dubowitz - European journal of paediatric …, 1997 - Elsevier
Duchenne and Becker muscular dystrophies are X-linked allelic disorders in which the
association of central nervous system dysfunction, typically in the form of mental retardation,
is a well recognized feature. They are both due to mutations in the dystrophin gene, whose
corresponding protein products are expressed both in the muscle and central nervous
system. We have observed an increased frequency of epilepsy in children with Duchenne
and Becker muscular dystrophy attending our clinic. Out of 254 boys with this condition (201 …
association of central nervous system dysfunction, typically in the form of mental retardation,
is a well recognized feature. They are both due to mutations in the dystrophin gene, whose
corresponding protein products are expressed both in the muscle and central nervous
system. We have observed an increased frequency of epilepsy in children with Duchenne
and Becker muscular dystrophy attending our clinic. Out of 254 boys with this condition (201 …