Microarray analysis of the transcriptional responseto single or multiple doses of ionizing radiation in human subcutaneous fibroblasts
BACKGROUND AND PURPOSE: Transcriptional profiling of fibroblasts derived from breast
cancer patients might improve our understanding of subcutaneous radiation-induced
fibrosis. The aim of this study was to get a comprehensive overview of the changes in gene
expression in subcutaneous fibroblast cell lines after various ionizing radiation (IR) schemes
in order to provide information on potential targets for prevention and to suggest candidate
genes for SNP association studies aimed at predicting individual risk of radiation-induced …
cancer patients might improve our understanding of subcutaneous radiation-induced
fibrosis. The aim of this study was to get a comprehensive overview of the changes in gene
expression in subcutaneous fibroblast cell lines after various ionizing radiation (IR) schemes
in order to provide information on potential targets for prevention and to suggest candidate
genes for SNP association studies aimed at predicting individual risk of radiation-induced …
