Hereditary leiomyomatosis and renal cell cancer: a syndrome associated with an aggressive form of inherited renal cancer

RL Grubb III, ME Franks, J Toro, L Middelton… - The Journal of …, 2007 - Elsevier
PURPOSE: Hereditary leiomyomatosis and renal cell cancer is a recently described
hereditary cancer syndrome in which affected individuals are at risk for cutaneous and
uterine leiomyomas, and kidney cancer. Our initial experience revealed the aggressive
behavior of these renal tumors, often with early metastasis, despite small primary tumor size.
We report the clinical characteristics and urological treatment of patients with hereditary
leiomyomatosis and renal cell cancer associated renal tumors. MATERIALS AND …