Bifidobacterium adolescentis IM38 ameliorates high-fat diet–induced colitis in mice by inhibiting NF-κB activation and lipopolysaccharide production by gut microbiota
SM Lim, DH Kim - Nutrition research, 2017 - Elsevier
Gut microbiota play essential roles in the regulation of human metabolism via symbiotic
interactions with the host. Prolonged consumption of high-fat diet (HFD) elevates the
Firmicutes to Bacteroidetes ratio and lipopolysaccharide (LPS) production by gut microbiota,
thereby increasing the probability of developing metabolic and immune disorders such as
obesity and colitis. The use of probiotics with anti-inflammatory properties has been
suggested to counteract this effect. Here, we tested whether Bifidobacterium adolescentis …
interactions with the host. Prolonged consumption of high-fat diet (HFD) elevates the
Firmicutes to Bacteroidetes ratio and lipopolysaccharide (LPS) production by gut microbiota,
thereby increasing the probability of developing metabolic and immune disorders such as
obesity and colitis. The use of probiotics with anti-inflammatory properties has been
suggested to counteract this effect. Here, we tested whether Bifidobacterium adolescentis …