There has recently been a resurgence of interest in the gastrointestinal pathology observed
in patients infected with HIV. The gastrointestinal tract is a major site of HIV replication,
which results in massive depletion of lamina propria CD4 T cells during acute infection.
Highly active antiretroviral therapy leads to incomplete suppression of viral replication and
substantially delayed and only partial restoration of gastrointestinal CD4 T cells. The
gastrointestinal pathology associated with HIV infection comprises significant enteropathy …