Tuberous sclerosis complex is a multiorgan syndrome manifesting with several benign and
malignant tumors. Complications arising from renal abnormalities are a leading cause of
death in patients with tuberous sclerosis complex. Renal cell carcinoma is relatively
uncommon, occurring in 2%-4% of patients with tuberous sclerosis complex syndrome, but
nonetheless can significantly contribute to morbidity and mortality. Extrarenal manifestations
of tuberous sclerosis complex, including within the chest, abdomen and central nervous …