[HTML][HTML] Systemic and mucosal antibody responses specific to SARS-CoV-2 during mild versus severe COVID-19
Background Whereas severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-
specific antibody tests are increasingly being used to estimate the prevalence of SARS-CoV-
2 infection, the determinants of these antibody responses remain unclear. Objectives Our
aim was to evaluate systemic and mucosal antibody responses toward SARS-CoV-2 in mild
versus severe coronavirus disease 2019 (COVID-19) cases. Methods Using immunoassays
specific for SARS-CoV-2 spike proteins, we determined SARS-CoV-2–specific IgA and IgG …
specific antibody tests are increasingly being used to estimate the prevalence of SARS-CoV-
2 infection, the determinants of these antibody responses remain unclear. Objectives Our
aim was to evaluate systemic and mucosal antibody responses toward SARS-CoV-2 in mild
versus severe coronavirus disease 2019 (COVID-19) cases. Methods Using immunoassays
specific for SARS-CoV-2 spike proteins, we determined SARS-CoV-2–specific IgA and IgG …