A potential role for B-cell activating factor in the pathogenesis of autoimmune myasthenia gravis

S Ragheb, R Lisak, R Lewis, G Van Stavern… - Archives of …, 2008 - jamanetwork.com
Objective To compare serum B-cell activating factor (BAFF) levels in patients with
myasthenia gravis (MG) with those in control subjects without MG. Design Case-control
study. Subjects Forty-three patients with MG were compared with control subjects without
MG. These included 48 healthy subjects, 25 patients with multiple sclerosis, and 3 patients
with amyotrophic lateral sclerosis. Results In all subjects studied, there was no correlation
between the serum BAFF level and the concentration of total IgG, IgA, or IgM. The BAFF …