Comparison of human fetal liver, umbilical cord blood, and adult blood hematopoietic stem cell engraftment in NOD-scid/γc−/−, Balb/c-Rag1−/− γc−/−, and CB-17-scid …
CM Lepus, TF Gibson, SA Gerber, I Kawikova… - Human immunology, 2009 - Elsevier
Immunodeficient mice bearing components of a human immune system present a novel
approach for studying human immune responses. We investigated the number, phenotype,
developmental kinetics, and function of developing human immune cells following transfer of
CD34+ hematopoietic stem cell (HSC) preparations originating from second trimester
human fetal liver (HFL), umbilical cord blood (UCB), or granulocyte colony-stimulating factor-
mobilized adult blood (G-CSF-AB) delivered via intrahepatic injection into sublethally …
approach for studying human immune responses. We investigated the number, phenotype,
developmental kinetics, and function of developing human immune cells following transfer of
CD34+ hematopoietic stem cell (HSC) preparations originating from second trimester
human fetal liver (HFL), umbilical cord blood (UCB), or granulocyte colony-stimulating factor-
mobilized adult blood (G-CSF-AB) delivered via intrahepatic injection into sublethally …