Diabetes mellitus in long-term survivors of childhood cancer: increased risk associated with radiation therapy: a report for the childhood cancer survivor study

LR Meacham, CA Sklar, S Li, Q Liu… - Archives of internal …, 2009 - jamanetwork.com
Background Childhood cancer survivors are at increased risk of morbidity and mortality. To
further characterize this risk, this study aimed to compare the prevalence of diabetes mellitus
(DM) in childhood cancer survivors and their siblings. Methods Participants included 8599
survivors in the Childhood Cancer Survivor Study (CCSS), a retrospectively ascertained
North American cohort of long-term survivors who were diagnosed between 1970 and 1986
as well as 2936 randomly selected siblings of the survivors. The main outcome was self …