Integrins are the major cell surface receptors for proteins in the extracellular matrix. These
receptors form major cell signaling centers that are bidirectional, communicating messages
between the cell and its environment. They are a large receptor family, with members well-
known to regulate cellular processes essential to both development and disease. In this
review we examine the literature regarding integrins in the lens. Here we cover integrin
function in lens cell differentiation, in the development of the lens and in protection of the …